The patient information for Accutane does acknowledge a link between the drug and IBD. Prescription oral acne medications include certain antibiotics, hormonal contraceptives, Accutane (isotretinoin), and Aldactone (spironolactone). All this considered, dermatologists acknowledge that Accutane has the potential for severe side effects. Prior to considering if Accutane is a treatment option for any form of acne, from mild to severe, it is essential to visit a dermatologist and discuss the pros and cons and risks and benefits of Accutane treatment to determine if Accutane is right for each individual’s circumstances. Accutane is available only from a certified pharmacy under a special program called iPLEDGE. This treatment comes in capsule form, and is designed to be taken once or twice a day, normally for a period of four to six months. Before and after photos start at 10:56In this video I talk about my experience with Accutane and my acne story. Roche would not call it an Accutane recall. Ya no me. It has been speculated that the drug Accutane (isotretinoin) may be connected to the development of inflammatory bowel disease (IBD). 00. The nose has the highest concentration and most active oil glands on the body, so someone on Accutane would theoretically see a difference in the thickness of the skin on the nose and, perhaps, a smaller looking appearance on the nose. Accutane is a prescription medication for individuals with severe acne. Although there can be many side effects to taking Accutane, you can help to minimize them by following these six simple skincare tips while you’re taking the medication. Patients who are pregnant or who plan to. Rabach says. When 40 greeted Danielle Pergament with her first-ever cystic breakouts, she learned a thing or two about isotretinoin (a. Additionally, nosebleeds, upset stomach, extreme sun sensitivity, and hair thinning are all common side effects. THIS ACCUTANE MEDICATION GUIDE IS AN IMPORTANT PART OF THE RISK MANAGEMENT PROGRAM FOR THE PATIENT. Accutane (isotretinoin) is in the family of retinoids. to bear. Accutane is an effective and safe isotretinoin drug for the treatment of acne. But unlike Accutane, adapalene is a topical treatment that comes in gel form. Accutane is needed for moderate to severe acne that has failed other treatments. The pictures below are both without. Accutane was a pill administered orally, so if that is a method of delivery you prefer, this may be worth considering. Isotretinoin: Think sun protection. Accutane alone is unlikely to cause hyperpigmentation because it decreases inflammation and acne, which is the opposite of what triggers hyperpigmentation. Then, the Supreme Court overturned Roe v. As a result, women who take Accutane between menarche and menopause should use two forms of contraception to. Please don’t use this medication, terrible mental side effects. This medication works by decreasing the size and activity of sebaceous glands, which are almost always located alongside a hair follicle — and HS develops, as noted above, when your hair. While diligent. Isotretinoin may cause side effects, including hair loss. It can reduce pore size and also reduce sebum production in your skin, making it less oily; and in turn, dryer. There are also topical forms of retinoids. However, this study also observed that 18% of. Accutane is an effective treatment for acne. I don’t understand how is this medication still in the market, with some many documented cases of mental side effects. Accutane (isotretinoin) is a highly effective acne treatment. Accutane). My vision went hazy, the room became bright, and my head started to throb. Allenby points out, just like topical vitamin A, isotretinoin will make your skin much more sensitive to the sun. Although approved by the U. Some doctors recommend waiting to do your course of Accutane. It may be prescribed for other uses. . If after all that the person still. These common side effects of isotretinoin capsules happen in more than 1 in 100 people. ACCUTANE use has been associated with a number of cases of pseudotumor cerebri (benign intracranial hypertension), some of which involved concomitant use of tetracyclines. Before your first month of treatment ends, you may experience a paradoxical acne flare, termed colloquially as “Accutane purge. Boosts self-confidence and quality of life. There are things you can do to help you cope with them: Dry skin, eyes, nose or lips. Dosage size of Accutane and length of the treatment. Accutane comes with some contraindications and possible side effects: 1. , but generic formulations are available. Follow her on Instagram @bellacacciatore_. “Dryness can be intense, and this is due to the fact that the medicine is decreasing sebum production as its primary action,” says Lauren Penzi, MD, board-certified. You'll need to enroll in iPledge to get your prescription; it's a requirement for everyone who is prescribed isotretinoin medications like Absorica, Amnesteem, Claravis, and Sotret. March, 2002. Accutane is a vitamin A derivative and belongs to a class of drugs called retinoids. The drug is a vitamin A derivative and addresses all four acne-causing areas. accutane medication. Accutane é um ácido retinóico oral que é composto de vitamina A em forma sintética. The iPLEDGE program is a program by the U. This medication is normally prescribed if the patient has not responded to ALL other treatment options. Intellectual and developmental disabilities. Accutane (isotretinoin) is a retinoid medication that is commonly used to treat severe acne. Absorica® and Accutane®: The dose is usually 0. Accutane (Isotretinoin) is used to treat severe types of Acne, such as nodular or inflammatory acne, where other medications with less potential for severe side effects have failed to help. Accutane, a drug that helps treat severe acne, contains isotretinoin. What to Expect. Isotretinoin is also called Accutane®. Microsoft Word - Accutane handout (isotretinoin). The best discounts in one place for. Treatment duration can last anywhere from 3-6 months, depending on severity and skin type, but the results should be long-lasting. By Emily Keel. You must not take Accutane if you are pregnant or may become pregnant during treatment. This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (such as benzoyl peroxide or clindamycin applied to the skin or. CAUSES BIRTH DEFECTS DO NOT GET PREGNANT. 1. The drug was approved by the US Food and Drug Administration (FDA) in 1982 to treat severe, resistant, nodular acne that is unresponsive to conventional therapy, including systemic antibiotics. Women must use two separate effective forms of birth control simultaneously for at least 1 month before treatment begins, during the entire course of. Isotretinoin is the only therapy that impacts on all of the major aetiological factors implicated in acne. However, people may experience mood changes while taking Accutane. Because of their young age, parents often need reassurance that Accutane can be safe for their 15 year old. 2. Berkowitz notes that surgeons have noted the “Accutane Nose Job” for quite some time and are even isotretinoin therapy as an adjunct to rhinoplasty. Accutane is a type of medication that treats severe or stubborn acne. 5 Min Read. Isotretinoin: Think sun protection. Areaware’s 3-D Terra-Cotta Coasters (or Trivet) $34 $45 25% off. Affiliation. 03 mg of Accutane per day (about 1/16 of. There were still the required blood work, as with. Heart defects. However, you might find that your old or current acne scars actually appear more pronounced after or during your time on Accutane. Accutane is the best medication available on the market for treating the most severe forms of acne. Common acne in teenagers starts with an increase in hormone production. When other treatments fail to clear the skin, isotretinoin may be an option. Isotretinoin is the only therapy that impacts on all of the major aetiological factors implicated in acne. Im about 2 weeks in and so far I have only had dry skin and headaches. Initially it made my acne worse than it had ever been which was discouraging for a few months. Dosage size of Accutane and length of the treatment. Isotretinoin Causes Severe Birth Defects and Miscarriage The Essential Info EXTREME CAUTION: Isotretinoin (Accutane®) interferes with fetal development and causes severe and life-threatening. Whether isotretinoin causes inflammatory bowel disease has been debated. How to Use. Because of these limitations, many acne sufferers attempt to seek treatment with Accutane through online health options. Accutane can be used to treat mild acne as well as severe and cystic acne. Medically Fact Checked. It is available in multiple brand and generic versions. In the first 2 weeks, your skin will start to feel less oily. Satisfaction. The drug has been FDA-approved since 1982 and the most common side effect is dryness of the skin, nose, lips and eyes. Possible side effect: Muscle aches after exercising may be more pronounced. Benzoyl peroxide and glycolic acid — a simple exfoliating alpha-hydroxy acid (or AHA) derived from sugar cane — make the DRMTLGY 24 Hour Acne Serum effective for many who are targeting particularly stubborn acne. 6% were classified as emotional lability. The cost for Accutane oral capsule 20 mg is around $186 for a supply of 30 capsules, depending on the. With a list of side effects like this, taking Accutane for acne seems daunting. A. 78 per 6, 10 Capsules Capsule, but is made up of the same active ingredients as Accutane. Isotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal abnormalities including cleft lips, ear and eye defects, and mental retardation. For many who experience a “purge,” it is generally. Nov 15, 2017. Two of the most sinister reported Accutane side effects, depression and inflammatory bowel disease, are the most widely debated in the medical community. Isotrentinoin (formerly known as Accutane) is the closest thing dermatologists and the medical community has for a cure to acne, but many people are wary of the drug because of reports of mental. Condition. It can cause your skin to flake and peel. Läkemedlet kan även användas mot svårartad iktyos och vissa cancerformer. Accutane (isotretinoin) is the active form of vitamin A, which has a powerful effect regulating sebum. Currently Available Formulations of Oral Isotretinoin. Be sure to use sunscreen that offers: Broad-spectrum protection (bottle may say “UVA/UVB protection”) An SPF of 30 or greater. 2. Start with a Smaller Dose and Gradually IncreaseAccutane (Isotretinoin) update after 4 months with before & after photos. Key types of birth control include tubal ligation, vasectomy, intrauterine device, hormone birth control patches or vaginal ring, estrogen-containing oral contraceptive; secondary forms are: vaginal sponge with spermicide, male latex condoms, diaphragm, or a cervical cap with spermicidal gel or foam. It is sometimes referred to as the “nuclear option” due to its ability to provide remission of acne in about 2/3 of people who take it, while at the. Chest Pain. Accutane is a drug that can cause severe birth defects, miscarriage, and stillbirths if you get pregnant while taking it, hence the monthly pregnancy tests and monthly checkups with a dermatologist. Taking isotretinoin capsules with other medicines and herbal supplements. Product Description. Both substances affect the neurotransmitters in the central nervous system. Pregnant women taking Accutane often face higher rates of spontaneous abortion and developing fetuses could be born with severe birth defects like craniofacial and heart defects. [2] [3] Patients, their doctors and their pharmacists are required by the FDA to register and use the iPLEDGE web site in order to receive. Whether or not the patient was on anti androgen treatment. Accutane is the brand name that most people use when referring to the oral acne medication isotretinoin. This pdf document contains the full prescribing information, including warnings, precautions, dosage, and administration of Accutane. S. Accutane, or Roaccutane in other countries (generic name Isotretinoin) is a powerful medication prescribed for people with severe acne. “Accutane, [the brand name of] isotretinoin, consists of giving an elevated dose of a form of vitamin A,” explains Dr. It may be prescribed for other uses. The Food & Drug Administration (FDA) also received reports of nearly a thousand cases of psychiatric issues between 2001 and 2009, along with several suicides. In Accutane’s defense (pun totally unintended,) the majority of lawsuits against them are by greedy, negligence, ambulance chaser lawyers. It can cause serious side effects, including birth defects, and requires careful monitoring by a doctor. Accutane has some effects that can be viewed as commonly occuring side effect like the extreme drying of the skin, but that drying is part of what actually helps get rid of acne, which is why most people get it on Accutane. In the evening, cleanse and moisturize. In the morning, Dr. The Benefits of Accutane. A reduction in reflexes - Alcohol and Accutane dull the brain as it promotes sedation which is especially dangerous if you work with heavy machinery or drive. Accutane, medically known as isotretinoin, is an anti-acne treatment used to treat the most severe and resistant forms of acne, typically cystic acne. acnes and has. It’s prescribed for severe acne only after trying other treatments first, such as oral medications like antibiotics and topical treatments. Other skin problems, including rashes, and mild itching. 5 to 1 milligram (mg) per kilogram (kg) of body weight per day, taken as 2 divided doses for 15 to 20 weeks. blurred vision or other changes in vision. Not like a little dry, but the kind of dry where your lips are constantly chapped and you’re prone to nosebleeds. Mechanisms and mode of action. Marinelli suggests. Isotretinoin is a prescription medication taken by mouth to treat severe cystic acne that has not responded to other treatments. These side effects are temporary: When you stop taking isotretinoin, these side effects tend to go away. Clearing Persistent Acne. It sold well for many years, but in 2009, Roche decided to remove Accutane from the U. For years. Common Differin side effects may include: dry, red, or scaly skin; feeling of warmth and mild stinging or burning; peeling skin; or. Photo: Trevor+Allison Photography. When taking the antibiotics, the acne would go away, but it would always come back. 6. Dosage, drug interactions, and pregnancy and breastfeeding safety should be reviewed. Take Accutane with a full glass of water to avoid it from getting stuck in your esophagus. They're typically used for moderate to severe acne vulgaris (the most common form of acne) This article describes the various oral acne treatment options, including the possible side effects and. A healthcare provider may prescribe this medication if other acne medications don’t work. The brand is no longer available in the United States. Accutane® has been known to cause severe birth defects, requiring ALL Accutane® patients to participate in the iPLEDGE® Program. and affects up to 50 million Americans annually. Buy at Areaware. Currently Available Formulations of Oral Isotretinoin. 5 to 1 milligram (mg) per kilogram (kg) of body weight per day, taken as 2 divided doses for 15 to 20 weeks. Like dry lips, peeling and flaking skin should subside after you stop taking the medication. 1-13 Isotretinoin is an oral medication that is typically prescribed in a 15-20 week course. There are additional meds you can get to combat the initial breakout: prednisone or an oral antibiotic called erythromycin. Accutane ( isotretinoin) and Retin-A ( tretinoin) Cream and Gel are forms of vitamin A called retinoids used for the treatment and prevention of severe acne. Accutane must not be used by females who are pregnant. The mechanism of action of the Accutane significantly. Isotretinoin must not be used to treat women who are able to bear children. Accutane for Acne User Reviews. Even though the manufacturer no longer sells Accutane in the United States, the generic versions are still commonly referred to as Accutane. However, it does come with a host of side effects. S. We learned through our investigation that reports of depression and suicide are not new. However, Accutane is no ordinary drug. “This. 5 to 1 mg per kilogram (kg) of the bodyweight daily. Isotretinoin is commonly called by its trade name Accutane, and it's a chemical compound derived. Nobody seems to have an answer to this. 1. Almost every acne sufferer that takes Accutane develops very dry skin. Just 41 per cent of the reports included. It's an oral. This medication has strong antitumor, anti-inflammatory and immunomodulatory properties making Accutane for acne a very effective. However, the new-and-improved drug absorbs into your system regardless of how much you eat (hence the name). It can take several months to see the full effects. An oil-free moisturizer with ceramides. zitstikaIsotretinoin (Accutane, sotret, claravis, amnesteem, myorisan, zenatane) is an expensive drug used to treat severe acne that has not responded to other therapy like antibiotics. Monthly labs and medical visits for an approximately six- month course Accutane treatment. It is important to carefully follow the instructions of your doctor and pharmacist when taking Accutane. See moreAccutane® (Isotretinoin) is a type of retinoid medication that treats severe acne. Acne vulgaris is one of the most common skin diseases in Europe, 1 and the most common in the USA, 2 affecting more than 80% of adolescents and young adults, 1 and persisting for decades in many cases. Accutane ajuda na cicatrização da acne, reduzindo o excesso de sebo da pele. If you have exhausted your acne treatments, you may want to consider taking Accutane. The lips also become very dry and can become chapped requiring frequent application of moisturizer. It. In total, 17,829 psychiatric events were reported across this time period, of which 42. Isotretinoin is still available as a generic or under several other brand names (Absorica, Amnesteem, Claravis, Myorisan, Zenatane). Isotretinoin is used to treat severe, disfiguring nodular acne. ” And the effects of Accutane have become something of a cautionary tale (Google at your own risk). To minimize the risk of irritation, keep your skincare routine as simple as possible. The medicine, which causes inflammation and increased acne, has a side effect known as "purging," which removes all oil, dust, debris, and dead skin cells from below the skin. But today, it is mostly used for the treatment of severe nodular acne. January 22, 2022. Vitamin A supplementation from natural sources and the infamous Accutane (a vitamin A derivative 13-cis-retinoic acid that WE DO NOT RECOMMEND) are two of the most well-known internal/oral treatments of acne. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar. Isotretinoin (Accutane®) October 1, 2021 page 2 of 2 Must be able to understand that severe birth defects can occur with use of isotretinoin. But patients, parents and doctors are. Find out how isotretinoin capsules treat acne and how to take them. S. Accutane is the brand name for the drug isotretinoin. Accutane is a prescription oral medication used to treat severe acne. The brand name Accutane is discontinued in the U. 70, which is 79% off the average retail price of $644. As this acne clears, scars often appear. For people with severe acne, one treatment option is isotretinoin, which is often prescribed under the brand name Roaccutane. Isotretinoin is also available to purchase under the. Warnings. Accutane has an average rating of 7. Limit all sun exposure while on Accutane, avoid direct sunlight, and always wear sunscreen with an SPF of at least 30, even on cloudy days. The drug causes serious side-effects, most notably birth defects. Meanwhile, plaintiffs have won an estimated $33 million in judgments against Roche for. I Just Finished 5 Months of Isotretinoin—Here’s How It Went. Adapalene. Accutane; Amnesteem; Claravis; Myorisan; Sotret; Zenatane; Descriptions. If you notice more hair shedding or thinner hair after. acnes bacteria on the skin, reducing skin oil production while improving cell turnover. 73% of reviewers reported a positive experience, while 14% reported a negative experience. Learn moreaguantar. S. Dermatologists also tell FOX 5 it can be used as an anti-cancer drug in some cases. Changes in Vision. The most common side effects from Accutane are chapped lips (90% of users), dry skin and itching (80%) and dry nasal pages or mild nosebleeds (80%). While Accutane has delivered amazing results for some, it's also been linked to an. Rachel Hosie. S. Accutane will make you dry. 14 Retinoids are a family of compounds derived from vitamin A. The Pros: Isotretinoin is an internal retinoid, which is a vitamin A derivative, and it's the only drug that addresses all four major acne-causing factors: It reduces skin oil production, improves. ) under the brand name Accutane for the treatment of cystic and nodular acne that is not responsive to other forms of treatment (Cunliffe et al. Accutane is a brand-name version of the drug isotretinoin. Isotretinoin is a derivative of vitamin A, which naturally occurs in our own bodies. Accutane is a type of medication that treats severe or stubborn acne. Accutane is the brand name for a medication called Isotretinoin, which is a high dose vitamin A treatment in pill form. Accutane is the brand name for the drug isotretinoin, a vitamin A derivative related to retinol and other retinoids used in skincare. In my case, I had deep and persistent acne scars on my cheeks as a result of years of pimple popping and picking in my teens. Accutane is the brand name for isotretinoin which is a powerful vitamin A derivative (retinoid) used to treat a number of serious skin conditions including skin cancers, psoriasis, rosacea, lupus and lichen planus. Isotretinoin is a medication closely related to vitamin A that’s most commonly used for severe nodular acne. Despite Accutane’s solid high rates of efficacy, the acne drug was considered a danger to female patients who became pregnant while using it. Both of these conditions have been linked. When we look at 17 studies from. As you can imagine, this poor scar healing applies to all of our cosmetic surgeries: facelift, rhinoplasty, blepharoplasty and many others. 5 mg/day: 64%. Skin purging looks like acne exacerbation. However, it can also cause serious birth defects and other side effects. While on Accutane, your skin becomes extremely sensitive, therefore limiting the types of products you can use within your skincare routine. Get blood tests regularly to make sure the medication is working properly. #11. It is a powerful Vitamin A derivative prescribed for patients who “have severe, nodular acne or cystic acne, those with acne resistant to traditional treatments. It is covered by most Medicare and insurance plans, but pharmacy coupons or cash prices may be lower. Accutane improved the overall texture and appearance of my skin in addition to clearing up my acne. está aguantando bien las presionesshe's holding o bearing up well under the pressure. Your doctor may adjust your dose as needed. Each person’s response to isotretinoin treatment is different, but most people begin to see the desired results within 2-3 months after starting to take the medication. Vitamin A is a key nutrient in the development and maintenance of healthy skin. Alcohol and Accutane are probably not a safe combination when it. Isotretinoin is the generic version of Accutane, a discontinued brand. 1 – 7 It results in a significant reduction in sebum production, influences comedogenesis, lowers. Several lawsuits have been brought against Roche Holding. Isotretinoin is still available as a generic or under several other brand names (Absorica,. After I got off of it I would see the occasional single new pimple here or there but it was very rare. Accutane causes severe birth defects when taken by pregnant women. if you're 23 and have acne, it means you'll likely continue to have it in the future because your acne is unrelated to puberty. Doctor’ visits, bloodwork and additional prescription drugs will affect overall costs. Isotretinoin, the generic name for Accutane, is a. You can take these capsules by mouth with a glass of water as directed. Accutane was the best thing I did, my skin has been flawless since my forth month. For this reason, it's very important to prevent pregnancy while taking the drug. I used to have horrible cystic acne, and also got prescribed several different antibiotics - Minocillin and Bactrim are what i could remember. In essence, Accutane works by reducing excess sebum, a thick, oily substance naturally. These include: 1. Isotretinoin — the prescription acne pill better known by the now-defunct brand name Accutane — can be confusing. AN ACCUTANE MEDICATION GUIDE MUST BE GIVEN TO THE PATIENT EACH TIME ACCUTANE IS DISPENSED, AS REQUIRED BY LAW. ACCUTANE et pendant au moins un mois après l’arrêt du traitement. Some serious side effects have been. This is a strict, government-required program that ensures people safely start and take isotretinoin. According to Allure, Isotretinoin is an “internal retinoid” that works to lessen inflammation, reduce the production of skin oil, improve cell turnover inside pores, and decrease the. I take isotretinoin. While there are many treatments available for acne, isotretinoin is considered to be the best option for severe and persistent acne. 34. It has long been suggested that the drug isotretinoin prescribed for hard-to-treat acne can cause depression. Accutane is used to treat a type of severe acne (nodular acne) that has not been helped by other treatments, including antibiotics. Allenby points out, just like topical vitamin A, isotretinoin will make your skin much more sensitive to the sun. Among women of childbearing age who were registered for iPLEDGE in 2006 and 2009 to 2010, the pregnancy rates ranged from 33 per 10,000 to 65 per 10,000. This is a life ruining side effect, which on its own should force the withdrawal of Accutane from being sold. That's precisely what happened to Kali Kushner, a 22-year-old who, over the last two years, has amassed more than 22,000 followers for sharing her journey using Accutane, a powerful form of acne. As I announced last September, with the encouragement of my. The “Accutane purge” can take may forms. What food or drink Accutane was taken with. Mild but persistent acne is a textbook case for accutane!Accutane offers several significant benefits for individuals struggling with severe acne. Accutane is available in the dosage form of 10, 20, and 40 milligrams (mg) soft gel capsules, which should be taken by mouth. Isotretinoin (eye-soh-tret-in-OH-in) is a prescription medication for severe acne. The shrinkage of the glands helps clear up the acne cysts and prevents. Accutane, Spironolactone, and tetracycline antibiotics have long been the most common systemic. Rachel Nazarian of Schweiger Dermatology Group in New York City. Accutane causes severe birth defects when taken by pregnant women. Originally approved by the United States (U. Developed by Hoffmann-LaRoche (Roche USA), Accutane brought in billions in revenue. Nose bleeds (resulting from dry mucous membranes) Joint pain and muscle pain. Isotretinoin (formerly sold under the brand name Accutane) is a medicine used for the treatment of severe cases of acne that haven't improved with other. Taken orally, Accutane is usually prescribed on a 4-month basis and has enjoyed a relatively high success rate in patients suffering from severe acne breakouts. However, Isotretinoin is a retinoid, which is so powerful that it literally. I took Accutane 2 years ago. Isotretinoin, better known as Accutane, is the acne drug of last resort. This medication is quite effective because it treats clogged pores, bacteria, inflammation, and oil production. Accutane's side effects were nasty, but for me, the results were worth it. Some hail isotretinoin, which offers a prolonged and even permanent cure for severe acne, as a miracle drug. In the first 2 weeks, your skin will start to feel less oily. Accutane is a drug that can cause severe birth defects, miscarriage, and stillbirths if you get pregnant while taking it, hence the monthly pregnancy tests and monthly checkups with a dermatologist. Accutane must not be used by female patients who are or may become pregnant. 3-0. Some serious side effects have been reported from. The classical recommended dose is 0. Materials and Methods: In this prospective, non-comparative study, 50 participants, both male and female, having moderate to severe acne vulgaris were enrolled and treated with isotretinoin at a dose of 20 mg/day (approximately 0. Accutane is not being absorbed. As many as 35 percent of infants exposed to isotretinoin during pregnancy will have birth defects. But after growing critics and an ever-increasing fury of Accutane lawsuits, the drug was taken off the market in 2009/2010. Accutane absolutely can cause extreme sexual dysfunction. Dr. Self-care tips: Take this medication at about the same time every day along with a meal that includes some fats. There are accusations that Accutane can cause some more serious side effects like depression, ulcerative collitis and. The more serious side effects of isotretinoin can have long-term or permanent effects. The gender of the patient. The drug is often very effective, but taking it while pregnant can cause serious, even deadly complications for babies.